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Hotels in South Main, Houston (TX), Texas are very affordable and a good option for staying in case you are planning a visit to Houston (TX), Texas. Below are some of the best hotels in South Main, Houston (TX), Texas offered by us for you to choose from. The rooms are very clean and comfortable with high-class amenities being provided to the guests. Book one from the below list of Houston (TX), Texas Hotels in South Main, Houston (TX), Texas at the best prices, starting from 86. Explore & book to grab exclusive deals and discounts now. Get Up to 20% (up to AED 400) Off* on hotel booking in Houston (TX), Texas with MakeMyTrip using coupon code : “SUPERSAVER” valid on 100,000+ Hotels. View More
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South Main, Houston (TX), Texas

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33 Properties in South Main, Houston (TX), Texas

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Residence Inn by Marriott Houston Medical Center/NRG Park

Astrodome | In South Main, Houston (TX), Texas
GymGym
Breakfast Included
Hurry! only last few rooms left at this price
Excellent4.6

Based on 412 Ratings

Cleanliness4.7

Room4.6

Hospitality4.6

(412 Ratings)

CAD 226

+ CAD 38 taxes & fees

Per Night

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SpringHill Suites Houston Medical Center/NRG Park

Astrodome | In South Main, Houston (TX), Texas
7 minutes walk to Smith Lands Station,
Swimming PoolSwimming Pool
GymGym
Free Shuttle ServiceFree Shuttle Service
Breakfast Included
Hurry! only last few rooms left at this price
Excellent4.4

Based on 974 Ratings

Location5

Cleanliness4.4

Room4.3

Hospitality4.5

(974 Ratings)

CAD 201

+ CAD 34 taxes & fees

Per Night

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Extended Stay America Suites Houston Med Ctr NRG Park Kirby

Astrodome | In South Main, Houston (TX), Texas
Swimming PoolSwimming Pool
GymGym
Free Cancellation till 4 hrs before check in
Breakfast Included
Good3.3

Based on 811 Ratings

Location4.4

Cleanliness3.3

Room3.2

Value For Money3.7

Hospitality3.6

(811 Ratings)

CAD 110

+ CAD 19 taxes & fees

Per Night

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Holiday Inn Express & Suites Houston Medical Center

South Main
Swimming PoolSwimming Pool
GymGym
Breakfast Included
Excellent4.6

Based on 920 Ratings

Cleanliness4.7

Room4.7

Hospitality4.6

(920 Ratings)

CAD 163

+ CAD 28 taxes & fees

Per Night

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Wingate Houston near NRG Park/Medical Center

Astrodome | In South Main, Houston (TX), Texas
Swimming PoolSwimming Pool
GymGym
Free Cancellation
Breakfast Included
Good3.3

Based on 811 Ratings

Cleanliness3.4

Room3

Hospitality3.7

(811 Ratings)

CAD 181

+ CAD 31 taxes & fees

Per Night

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Quality Inn & Suites NRG Park - Medical Center

South Main
Swimming PoolSwimming Pool
GymGym
Free Shuttle ServiceFree Shuttle Service
Breakfast Included
Hurry! only last few rooms left at this price
Good3.2

Based on 971 Ratings

Location4.5

Cleanliness3.1

Room2.9

Hospitality3.6

(971 Ratings)

CAD 98

CAD 85

+ CAD 14 taxes & fees

Per Night

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Staybridge Suites Houston - Medical Center

Braeswood Place | In South Main, Houston (TX), Texas
GymGym
Free Cancellation
Breakfast Included
Hurry! only last few rooms left at this price
Excellent4.4

Based on 664 Ratings

Cleanliness4.5

Room4.5

Hospitality4.5

(664 Ratings)

CAD 233

+ CAD 40 taxes & fees

Per Night

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Holiday Inn HOUSTON S - NRG AREA - MED CTR

Astrodome | In South Main, Houston (TX), Texas
Swimming PoolSwimming Pool
GymGym
Free Shuttle ServiceFree Shuttle Service
Hurry! only last few rooms left at this price
Very Good4.0

(951 Ratings)

CAD 159

+ CAD 27 taxes & fees

Per Night

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Wyndham Houston near NRG Park/Medical Center

Astrodome | In South Main, Houston (TX), Texas
Swimming PoolSwimming Pool
GymGym
Free Cancellation till 24 hrs before check in
Very Good3.7

Based on 876 Ratings

Cleanliness3.7

Room3.3

Hospitality4

(876 Ratings)

CAD 182

+ CAD 31 taxes & fees

Per Night

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Candlewood Suites HOUSTON MEDICAL CENTER

South Main
Swimming PoolSwimming Pool
GymGym
Free Cancellation
Very Good3.8

Based on 727 Ratings

Location4

Cleanliness4.1

Room3.9

Value For Money3.8

Hospitality4

(727 Ratings)

CAD 109

+ CAD 19 taxes & fees

Per Night

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Hotel Ylem

Braeswood Place | In South Main, Houston (TX), Texas
Free Shuttle ServiceFree Shuttle Service
Breakfast Included
Very Good4.2

Based on 1879 Ratings

Location4.8

Cleanliness4.2

Room4.1

Hospitality4.3

(1879 Ratings)

CAD 96

+ CAD 23 taxes & fees

Per Night

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Comfort Suites Houston near Medical Center- NRG Stadium

Braeswood Place | In South Main, Houston (TX), Texas
Swimming PoolSwimming Pool
GymGym
Breakfast Included
Hurry! only 1 room left at this price
Very Good4.2

Based on 764 Ratings

Location4.5

Cleanliness4.4

Room4.2

Hospitality4.4

Value For Money4

(764 Ratings)

CAD 159

CAD 132

+ CAD 22 taxes & fees

Per Night

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Scottish Inn and Suites NRG Park/Texas Medical Center - Houston

Astrodome | In South Main, Houston (TX), Texas
Free ParkingFree Parking
Hurry! only 1 room left at this price
Very Good4.2

(98 Ratings)

CAD 112

+ CAD 19 taxes & fees

Per Night

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Astro Best Inn

South Main
Free ParkingFree Parking
Very Good3.6

(148 Ratings)

CAD 100

+ CAD 17 taxes & fees

Per Night

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Motel 6 Houston, TX - Medical Center/NRG Stadium

South Main
Elevator/LiftElevator/Lift
Free ParkingFree Parking
Free Cancellation till 24 hrs before check in
Hurry! only 1 room left at this price
Good3.0

Based on 955 Ratings

Location3.7

Cleanliness3.1

Room2.9

Hospitality3.5

(955 Ratings)

CAD 77

+ CAD 13 taxes & fees

Per Night

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Americas Best Value Inn NRG Park Medical Center

Braeswood Place | In South Main, Houston (TX), Texas
Swimming PoolSwimming Pool
Free Shuttle ServiceFree Shuttle Service
Free Cancellation till 24 hrs before check in
Very Good3.8

Based on 639 Ratings

Location3.5

Cleanliness3.9

Room3.6

Value For Money2.5

Hospitality4.1

(639 Ratings)

CAD 154

+ CAD 26 taxes & fees

Per Night

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Studio 6 Houston, TX – Medical Center NRG Stadium

South Main
Elevator/LiftElevator/Lift
Free ParkingFree Parking
Free Cancellation till 24 hrs before check in
Good3.0

Based on 127 Ratings

Cleanliness3

Room2.8

Hospitality3.2

(127 Ratings)

CAD 80

+ CAD 14 taxes & fees

Per Night

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Entire Apartment

Lovely 1BR Apartment near Medical Center & NRG

Braeswood Place | In South Main, Houston (TX), Texas
Entire Apartment
| 1 Bedroom | Sleeps 4 guests
Entire Apartment

Entire Apartment

Entire Property

Get complete access to all bedrooms, bathrooms, living room, kitchen and more!

Please refer to Property Layout section on the Details page for access information for All spaces

Free ParkingFree Parking
Hurry! only 1 room left at this price

CAD 84

+ CAD 12 taxes & fees

Per Night

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Entire Apartment

1-Bedroom Haven in Murworth, Close to Medical Center

Braeswood Place | In South Main, Houston (TX), Texas
Entire Apartment
| 1 Bedroom | Sleeps 4 guests
Entire Apartment

Entire Apartment

Entire Property

Get complete access to all bedrooms, bathrooms, living room, kitchen and more!

Please refer to Property Layout section on the Details page for access information for All spaces

Free ParkingFree Parking
Hurry! only 1 room left at this price
Very Good3.8

(10 Ratings)

CAD 100

CAD 84

+ CAD 12 taxes & fees

Per Night

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Entire Apartment

Lovely Oasis Pool Gym Wi-Fi Free Parking

Astrodome | In South Main, Houston (TX), Texas
Entire Apartment
| 1 Bedroom | Sleeps 6 guests
Entire Apartment

Entire Apartment

Entire Property

Get complete access to all bedrooms, bathrooms, living room, kitchen and more!

Please refer to Property Layout section on the Details page for access information for All spaces

Swimming PoolSwimming Pool
Free ParkingFree Parking
Hurry! only 1 room left at this price
Average2.2

(3 Ratings)

CAD 131

+ CAD 196 taxes & fees

Per Night

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Properties In South Main, Houston (TX), Texas

Properties In Houston (TX), Texas